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Ask your health care provider if Allopurinol  may interact with other medicines that you take. After you have been taking allopurinol regularly for several months, the attacks may stop completely. This pathway of Thioguanine inactivation is not dependent on the action of xanthine oxidase, and an inhibitor of that enzyme (such as allopurinol) will not block the detoxification of Thioguanine even though the inactive 6-thioxanthine is normally further oxidized by xanthine oxidase to thiouric acid before it is eliminated. You will need to discuss the benefits and risks of using Allopurinol  while you are pregnant. There are no data with Augmentin and allopurinol administered concurrently.

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