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A 63-year-old man receiving allopurinol for gout developed progressive uremia, proteinuria, edema, and purpura after beginning quinidine therapy. Do not use this medication if you are allergic to didanosine, or if you are also taking allopurinol (Zyloprim) or ribavirin (Rebetol, Ribasphere, Copegus Virazole). The total amount of allopurinol is usually not more than 800 mg a day. There is no specific information comparing use of allopurinol in the elderly with use in other age groups. Allopurinol will help prevent gout attacks only as long as you continue to take it. A reaction with another antigout drug, allopurinol, may cause a rash.

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